Physiolibrary.Organs.Heart

Heart Components

Package Content

Name	Description
Heart
Components
Examples
References	References

Physiolibrary.Organs.Heart.Heart

Information

Calculates hearth pumping (left and right atria and ventricles, as wel as coronary circulation). By pressure-flow connectors communicate with pulmonary and systemic circulation.

Blood volume (and pressure) distributions between

right/left atrium and
right/left ventricle.

Generate average blood flow throught ventricles.

On the contrary of Tom Coleman models: coronary circulation outflows to right atrium, average blood volume in the hearth are calculated more simple (with the same results in steady state).

New heart energy balance

left: 1.41 W(const BasalCals), HR*P*V 1.4 W

right: 0.21 W (const BasalCals), HR*P*V 0.19 W

Effeciency by

https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.106.660639

is 25% (basal metabolism included).

Optimal values:

Left heart:

90mmHg= 12000Pa

75ml = 0.000075m3

75bpm = 1.25Hz

= 1.125 W (mechanical work)

4.5 W (total energy for 25% effeciency with basal metabolism)

1.41 W (basal metabolism)

36% motion effeciency without basal metabolism (new parameter for heart)

Right heart:

12.4mmHg=1653Pa

75ml= 0.000075m3

75bpm=1.25Hz

= 0.155 W (mechanical work)

/0.25 = 0.62 W (total energy for 25% effeciency with basal metabolism)

0.21 W (basal metabolism)

38% motion effeciency without basal metabolism (new parameter for heart)

Old estimation of heart energy balance

left: 1.67 W (const MotionCals) , 6.07 W (const HeatCals), 1.41 W(const BasalCals) = 7.74 W + 1.41 W = 9.15 W

right: 0.35 W (const MotionCals) , 1.19 W (const HeatCals), 0.21 W (const BasalCals) = 1.54 W + 0.21 W

Extends from Physiolibrary.Icons.Heart.

Parameters

Name	Description
replaceable package Blood	Blood medium model
NormalPericardiumPressure	Typical value of pericardium cavity pressure (relative to environment ambient pressure) [Pa]
Sinoatrial node
BaseHeartRate	Base heart rate [Hz]
SA_SympatheticRateIncrease[:, 3]	Heart rate increase on sympathetic neural activity
SA_ParasympatheticRateIncrease[:, 3]	Heart rate increase on parasympathetic neural activity
Baroreceptors
AdaptationOnNA[:, 3]	Neural activity effect based on mean atrial pressure change
AdaptivePressure	Initial value of adapted mean atrial pressure [Pa]
AdaptationTau	Delay coefficient of baroreceptors adaptation [s]
Right heart
Coronary blood suply
RightCoronaryLarge	Conductance of lagre coronary vessels [m3/(Pa.s)]
RightCoronarySmall	Conductance of small coronary vessels [m3/(Pa.s)]
Atrium
RightAtriumBlood_initial	Initial blood volume in right atrium [m3]
RightAtriumCompliance	Mean compliance of right atrium [m3/Pa]
Ventricle
RightVentricle_initial	Initial blood volume in right ventricle [m3]
RightVentricleBasicCompliance	Basic compliance od right ventricle [m3/Pa]
RV_K	time adaptation coeficient of average ventricle blood volume [Hz]
Diastole
RV_NormalEndDiastolicVolume	Typical value of blood volume in ventricle after filling [m3]
RV_NormalFillingPressure	Typical value of filling pressure relative to pericardium pressure [Pa]
RV_stiffnes	Relative stiffnes (1 if normal) [1]
RV_n_Diastole	Exponent of P-V characteristic of EDV curve on filling pressure [1]
Systole
RV_NormalSystolicPressure	Typical value of systolic pressure relative to pericardium pressure [Pa]
RV_NormalEndSystolicVolume	Typical value of blood volume in ventricle after ejection [m3]
RV_additionalPressure_Systolic	Pressure difference between mean and systolic pressure [Pa]
RV_contractilityBasic	Relative contractility (1 if normal) [1]
RV_n_Systole	Exponent of P-V characteristic of ESV curve on systolic pressure [1]
Left heart
Coronary blood suply
LeftCoronaryLarge	Conductance of lagre coronary vessels [m3/(Pa.s)]
LeftCoronarySmall	Conductance of small coronary vessels [m3/(Pa.s)]
Atrium
LeftAtriumBlood_initial	Initial blood volume in left atrium [m3]
LeftAtriumCompliance	Mean compliance of left atrium [m3/Pa]
Ventricle
LeftVentricle_initial	Initial blood volume in left ventricle [m3]
LeftVentricleBasicCompliance	Basic compliance od left ventricle [m3/Pa]
LV_K	time adaptation coeficient of average ventricle blood volume [Hz]
Diastole
LV_NormalEndDiastolicVolume	Typical value of blood volume in ventricle after filling [m3]
LV_NormalFillingPressure	Typical value of filling pressure relative to pericardium pressure [Pa]
LV_stiffnes	Relative stiffnes (1 if normal) [1]
LV_n_Diastole	Exponent of P-V characteristic of EDV curve on filling pressure [1]
Systole
LV_NormalSystolicPressure	Typical value of systolic pressure relative to pericardium pressure [Pa]
LV_NormalEndSystolicVolume	Typical value of blood volume in ventricle after ejection [m3]
LV_additionalPressure_Systolic	Pressure difference between mean and systolic pressure [Pa]
LV_contractilityBasic	Relative contractility (1 if normal) [1]
LV_n_Systole	Exponent of P-V characteristic of ESV curve on systolic pressure [1]

Connectors

Name	Description
replaceable package Blood	Blood medium model
rightAtrium	blood inflow to right atrium
rightVentricle	blood outflow to pulmonary circulation
leftVentricle	blood outflow to aorta
leftAtrium	blood inflow to left atrium
Pericardium	pericardium pressure [Pa]
Sympathicus	Ganglia general neural activity [Hz]
Parasympathicus	Vagus neural activity [Hz]
AtrialLowPressureReceptors	[1]

Physiolibrary.Organs.Heart.References

References

Information

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Extends from Modelica.Icons.References (Icon for external references).

Automatically generated Wed Oct 11 14:54:26 2023.